Researchers found that breast milk from mice lacking the key complement protein made their offspring highly susceptible to Citrobacter rodentium, a bacteria that causes diarrhea in mice. This suggests that the complementary components of breast milk directly destroy certain gut bacteria, creating a less favorable environment for Citrobacter rodentium infection. This activity does not require antibodies, unlike the typical functioning of complement proteins.
The researchers also confirmed that human breast milk contains these complement components that show similar activity against certain bacteria. These results shed light on the protective mechanisms of breast milk against some bacterial infections.
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Source: Ferra
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