The new tool will help us understand bacterial infections because such electrical signals are involved in a process that causes some bacteria to survive and become immune to antibiotics.
The team used the molecule Ziapin2, which binds to bacterial membranes and changes its structure when exposed to light.
“We found that bacteria exhibit an electrical pattern known as hyperpolarization when exposed to blue-green light. We showed that Ziapin2 causes electrical changes in bacteria by causing special channels to open,” said Munehiro Asalli, one of the study’s authors. cells.”
The scientists say that although this technique is at an early stage, it could help better understand microbial phenomena such as cell-to-cell signaling, antibiotic activity and antimicrobial resistance in the future.
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