Scientists from the Institute of Automation and Electrometry of the Siberian Branch of the Russian Academy of Sciences have developed nanosensors that can be used for the early diagnosis of glioma, a brain tumor. These sensors operate in the terahertz frequency range and can detect markers associated with this tumor type. Scientists used metamaterials, artificial materials with special optical properties, to create these sensors. They have successfully experimented with glioma markers, showing that nanosensors can be useful in the early diagnosis of this disease.
Glioblastoma is a difficult tumor to detect and can only be detected by MRI in advanced stages. Nanosensors open the possibility of early detection of glioma. These sensors were created using nanolithography by engineers from the Institute of Semiconductor Physics of the Siberian Branch of the Russian Academy of Sciences. Scientists have found that some cancer markers have special properties in the terahertz spectral range. One such glioma marker, hydroxyglutarate, can be used to determine glioma stages.
It turns out that the sign isomers have resonance frequencies in the terahertz range and the sensors can distinguish them using spectroscopy. The sensors are highly sensitive due to the concentration of the electromagnetic field in the nanoresonator, which makes it possible to interact with molecules effectively. Each isomer has its own unique resonance frequency, so sensors are designed for each isomer, allowing you to measure the balance and diagnose disease. Currently, the developed devices are being tested, and in the future such a diagnostic system can be used to analyze a drop of blood for the presence of glioma markers and determine their balance, which will help identify a pathological condition.
Source: Ferra
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