In MS, inflammation prompts the immune system to remove the protective layer of myelin around nerve fibers in the cerebral cortex, which causes disruption of electrical signals.
This cortical damage is associated with long-term disability in MS patients, including cognitive decline. While current treatments for MS mainly focus on fighting inflammation, a new study shows that estriol can repair myelin damage in a mouse model of MS, raising hope for future therapeutic interventions.
This study marks the first identification of a treatment that can restore myelin in the cerebral cortex and reverse the effects of MS.
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Source: Ferra
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