The innovation is based on calcium phosphate cement, which is close in composition to natural bone tissue and is biocompatible. This porous material was deposited on the surface of a titanium plate using an electrochemical method and ultrasound. A solution of the antitumor drug 5-fluorouracil, widely used in oncology, was loaded into the pores of the cement.
To prevent the drug from being released too quickly, scientists applied a protective layer of biodegradable polymers consisting of lactic and glycolic acids. This polymer slowly decomposes in the body and provides a long-term therapeutic effect. The developed coating has the potential to be used not only in oncology, but also in traumatology and dental prosthetics.
Source: Ferra
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