The human auditory mechanism is associated with the sensory system of sea anemones. The pou-IV gene in the tentacles of the sea anemone (Nematostella vectensis) is important for the tactile senses of this well. Nematostella vectensis belongs to Cnidaria, close relatives of Bilateral animals, which suggests that we had a common ancestor who lived 748-604 million years ago, and this gene was probably needed for the development of touch
The study opens up new horizons in the study of the genetics of anemones, and also suggests that modern Precambrian astronauts have the mechanism of our hearing. In vertebrates, hearing receptors are absorbed by hair cells located in bundles of finger-shaped organs, stereocilia perceive the sensation that we hear as sound. Mammals need Pou-IV for cell growth – mice with artificially disabled for born cells
In anemones, similar hair cells are present on the tentacles. Scientists have decided that it is this gene in Nematostella vectensis. For this gene, they turned off: fertilized anemone eggs, especially blond cas9 and observed in embryos and already adults. The mutants showed abnormal development of hair cells on the tentacles, and they did not respond to stimuli. They also show symptoms. A gene similar to polycystin 1 in vertebrates, needed to detect fluid flow in the kidneys. The feeling that fluid flow plays a big role in the life of marine animals.
In General, Research shows that pou-iv was required for mechanosensory cells in a common ancestor of cnidarians and bilateral animals. However, even earlier genetic disorders are needed for a deeper analysis. Exactly when the role of pou-IV became important in animal evolution remains unresolved – more comparative studies on Placozoans (Lamellars) and Sponges.
Source: Tech Cult
