The researchers analyzed the results of 98 randomized controlled trials conducted between 1964 and 2021 in 15,134 adults with acute low back pain. They studied 69 different pain medications, including nonsteroidal anti-inflammatory drugs, acetaminophen/paracetamol, opioids, anticonvulsants, antidepressants, skeletal muscle relaxants, and corticosteroids.
Surprisingly, there has been a lack of conclusive evidence that analgesics work better than placebo, and an even greater lack of medical research on effectiveness:Despite more than 60 years of research, we are still not convinced that any pain reliever provides meaningful relief from low back pain.”– said one of the authors of the new study.
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Source: Ferra
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