‘Chimera’ monkey baby with high amounts of stem cells has green eyes and fluorescent fingers

First time, A chimeric monkey with large amounts of cells derived from embryonic stem cells was engineered alive.

The baby monkey’s cells come from two different embryos, which means: they are genetically differentturning the young primate into a ‘chimera’.

stem cell line

The term ‘stem cell line’ refers to a population of stem cells obtained from a single source that can be grown and propagated in the laboratory.

Although scientists have previously conducted similar experiments on rats and mice, replicating this process with more complex animals such as monkeys has proven difficult.

Zhen Liu, author of the study, stated that this has been a long-pursued goal in the field. He emphasized that this research is not only about the subject. Understanding naive pluripotency in other primatesIt also has practical implications for genetic engineering and species conservation, including for humans.

‘Chimeric’ monkey

Researchers created a “chimeric” monkey by carefully nurturing and developing the baby primate in the mother monkey’s womb.

Based on genetic testing and various techniques, Most of the baby monkey’s body consists of cells derived from given stem cells.

green fluorescent protein

Researchers to determine stem cell lineage labeled with green fluorescent protein and placed a specific group of these cells into very young monkey embryos, which were then transplanted into female monkeys. This resulted in 12 pregnancies and six live births.

Tests showed that a live-born monkey and a dead fetus had a mixture of injected stem cells and monkey cells.

The three-day-old baby monkey showed green fluorescent markings on its fingertips and eyes..

Researchers examining various organs of the living monkey observed that they contained between 21% and 92% of cells originating from injected stem cells.

The future of stem cell research

Scientists suggest that there are variants such as: Health of monkey mother embryo and properties of stem cells This may affect the success of the process. They advocate examining individual cells at different stages of development to improve understanding.

Study co-author Miguel Esteban emphasized that this discovery increases our understanding of how these stem cells work in monkeys and their developmental potential in primates, including humans.

Stay up to date with the latest scientific research at TecMundo. If you wish, take the opportunity to learn about “Living Robots” created from frog stem cells.