Many of the soda that we consume every day were born as drugs. Or they were even prohibited by their content in substances that can be considered drugs. This is exactly the case 7upRecently a pharmacist, known on social networks as Heart failure He told about this in the video Tiktok, which is repeated by several media. And this is not for the smaller ones, because the historical relationship between this drink and bipolar disorder are the most curious. Track: it is connected with LItio, But the story goes much further.
The reality is that 7up, originally known as Lithic lem soda with lemon limeHe was not born for the treatment of bipolar disorder. In fact, this has never been used for such a thing. Yes, this was developed to treat a hangover, because it was believed that this helped reduce the harmful effects Excess alcohol In fact, on their first label in 1927, the words “wake up” or, in Spanish, “Raise!” Presumably, if after some other points I have not raised the drinking name, no one will be.
Logically, the difficulty of memorizing it did not have a very good marketing. Therefore, in 1936, it changed to 7up, which we all know. But in fact, it was in 1949, when his curiosity was discovered Relations with bipolar disorder.
Lithuanian history and bipolar disorder
In the past, what is now called bipolar disorder Depressive manic psychosis. It was so because patients alternated the state of great euphoria with other unpredictable depression. In the article Bi -bi -x which also has talk about 7up, case Mr. G.., The person who was accepted into psychiatry in 1968 for periods of depression, with suicid thoughts and moments of euphoria, in which his great interest was to meet with the president of the government of his country.
Like him, many patients were in those sanatoriums in which at that time they already began to use some drugs. However, in the previous decades, it was normal to resort to Electochical and lobotomyThe field of Mr. J. was able to completely normal life when lithium was tested with him. This psychotropic was discovered in 1949, but this was not yet widespread, so its doctors found time to resort to it.
The fact is that when this conclusion was made in 1949, its intended intendor was not taken very seriously. It was John Cade, Young doctor, veteran of the Second World War. He worked as a psychiatrist in a hospital in Melbourne, in Australia, but his passion was not only to treat patients. He also constantly defended the importance of research. Therefore, since not a single laboratory was placed at his disposal, he installed his own hospital cuisine.
Kitchen tests
There, Kade decided to try some drug candidates in guinea pigsI was very interested in the field in depressive manic psychosis. It was not normal to resort to medication for treatment, but he believed that this was possible. I had this hypothesis due to what you learned, reading Research on the fall. This disease from the accumulation of uric acid of blood sometimes caused manic symptoms. Kade knew that some doctors managed to reduce uric acid level by treating lithium salts, such as Litius citrate. Therefore, he thought that, perhaps, this can serve that later it would be known as a bipolar disorder.
Cuban injections significantly improved their mood. But, as we know today, something works on laboratory animals, does not mean that it will also do it with people. Therefore, although he was not perceived very seriously, he managed to check in patients with the specified disorder, getting very good results.
What should 7UP do?
Thanks to John Cade’s research, we know that lithium is useful for the treatment of bipolar disorder. However, in his essay he did not check Adequate dose. This substance began to introduce to patients without any dose control, so there are few in many cases poisoning. Side effects were very serious.
Therefore, in some countries, its use has become prohibited directly. The most curious that it was not only forbidden as a drug. Also 7up left the market.
But these prohibitions were not forever. Other studies continued to analyze the perfect dose for obtaining advantages without secondary effects or, at least, were unlikely. It is currently used to treat bipolar disorder, although not as before.
Where he is no longer in 7up, where instead of lithium -cocytrate it is now used Sodium citrate. Does this mean that this is no longer suitable for our mood? The truth is that it has never been. Doses were not enough.
Source: Hiper Textual
