A 3D -tobate materials and items This can have many used biomedicines. They were printed from the stains of the skin and teeth on much more complex organs. Applications that this can have in the future, even partially already at present, are immeasurable simply in order to be able to print all these organs and tissues in the laboratory. However, a team of scientists from Kaltekh It was another step, printed materials on demand Right inside the bodyThey did it in the field Mice and rabbitsTherefore, we will have to wait to see whether it is possible to do it with people; But while the results are fascinating.
It is true that this is not the first time when 3D -toy inside the body. However, there is a big difference, since before it was done with infrared radiation, This cannot reach the deep layers, so the process has occurred A little below the skin. These scientists have done this with ultrasound, which allows you to achieve much deeper points, such as muscles and organs.
As a result, there is a lot of use of this procedure, from the impression of injured tissues, only where they are necessary for the distribution of drugs for cancer, passing through wiring for devices such as a pacemaker.
3D -toy directly where it is necessary
These scientists managed to make a 3D impression directly into the body of mice and rabbits, simply introducing a biostant.
It contains Variable ingredientswhich depends on the printing of the material, but also two components that should be Always presentThe field on the one hand, Polymer chains It acts like raw materials. And on the other hand, Agents with reticulants. These are agents whose function is to generate chemical bonds between linear molecules. Thus, trimer molecules with new functions were obtained.
If all this were directly introduced, reticulating agents will begin to collect polymers to lead to the fact that biomaterial is directly. This is not convenient, because it is necessary in a particular part of the body. That’s why Retikulative agents are packaged in liposomesa kind of lipid capsules that break only with an increase in temperature to some 41’7 ºC.
With the exception of extreme fever, the human body, such as used animal models, usually does not reach this temperature. Therefore, liposomes remain closed until the heat is used artificially. This is precisely the function of ultrasound.
Endless applications
Due to the very accurate control of the ultrasound beam, these scientists have reached a three -dimensional impression of materials with complex forms, such as Star or tearIn addition, they got it right in the desired place.
In fact, they saw this thanks to another very smart procedure. And they used Small gaseous bubbles They change their contrast when exposed to chemical reactions, with which agents -recoving agents begin to collect pieces. Then these signals are collected by ultrasound itself.
Thus, it can be observed if the liposomes opened in the right place at the right time and, of course, also if they worked properly.
Given its proper functioning, scientists expect many applications to have, especially It is quoted earlier. But first of all, they have high expectations in Accurate administration of cancer drugs. In fact, they have already conducted a test in Cultures of human cells With bladder cancer. By introducing biotinta, which in this case brought the drug called incapsulated DoxorubicinIt was slowly released for several days. If the result is reproduced in patients, less chemotherapy will be required, and side effects will be reduced.
At least in the models used is not toxic
Another important fact that was seen in animals is that this biotin is not toxic. Therefore, 3D -to -befit can be performed safelyIs this a field too for people? We will have to wait to find out, but it is clear that these types of methods will play an important role in the future.
Source: Hiper Textual
