If there is an animal that can help us improve in the area Regenerative medicine, This is undoubtedly axolotl (Ambystoma Mexicanum) This sympathetic animal has the ability to promote Limbs regeneration and even internal organs Entires when you lose them. This is what was known for many years. Therefore, like other animals, such as Salamander, it takes a lot of time from the point of view of scientists. However, now there is a new conclusion that is a giant step in finding the procedures that allow us to imitate the axolot.
And we knew what AAGLE reaches, but not how he achieved it. Now a team of scientists from Universities of the North -East and Kentukki I outlined what a molecule is, which indicates Fibroblasts where they should work to fulfill The regeneration of the limbsIn addition, they proved a trick to form a missing part. If the injury occurred on the shoulder, a whole hand. If this happened at the elbow, only from the forearm.
What also attracted the attention of the authors of this study is that people We have the same cells and molecules. That is, we have all the material to regenerate the limbs of the axolot. The problem is that it seems that we have different signals. There is a key. The thread that they must pull from this moment. Everything is achieved, but they took a giant step.
Alarm of tricks for regeneration of the limbs
These scientists have proved that Retinic acid This is vital for the regeneration of the limbs to be made in Ajolot. Yes, the same thing that cosmetics carries to promote the regeneration of the skin. In the background should not surprise us.
It is logical, the regeneration of the limbs is something much more complicated. These scientists confirmed that The trick in the gradientThe retinoic acid field is found in the limbs of the axisation after the gradient from a larger to a lower concentration when it moves away from the body. For example, in the midst of what will be a shoulder, it has a large amount of retinoic acid and a reduced concentration of the enzyme, which is responsible for its decomposition. When we go down your foot until we reach our fingers, the opposite arises. The concentration of retinoic acid is reduced by the concentrate of the enzyme that destroys it.
Thus, when an injury occurs, Fibroblasts They receive signals that will vary depending on the concentration of available retinoic acid. The higher the injury occurred above. This is what is superly effectively confirmed in the laboratory.
What about people?
People have retinoic acid and fibroblasts. We have everything you need for the regeneration of the limbs. However, when a person loses its limb, only one Collagen scar In the area of defeat. Nothing more. This, as the authors of the study investigated, is due to the fact that the signals that are sent, and the interpretation that they make from them, are different cells.
Therefore, at the second stage of their research, they want to focus on studying these signals. Both those that are radiated by people, and from Ajolot. Thus, perhaps the day comes when we can restore the full hand. Now it seems to be science fiction, but the axolot, with all its memes and this good face, can give us the key.
Source: Hiper Textual
