Male tablet is much closer after this clinical test

Let’s be honest. The search for a pill for male contraception is carried out with a much larger number of signs than that of the woman herself. With a woman: do they not get pregnant, but increase the risk of thrombosis, myocardial infarction and stroke? Forward, continue. With the male: it seems that they do not produce sperm, but they came out of acne. It is better to continue investigating. If we represent this with the meme of a large dog and a small dog, everything makes much more sense.

That is why we were waiting for this pill for men who never arrive for decades. However, according to the results of the clinical test, there are many close ones It is recently carried out by Tychoe Therapeutics.

This Male contraceptive tablet without hormonesThe field of attempts at a hormonal version, similar to the fact that in the past they did not encounter in the past. There were many attempts, all of them are canceled for side effects of various severity. Some, logically, should stop clinical trials, as in the case of tablets that caused so many mood effects that even cases of suicide. In other cases, on the other hand, the seriousness of side effects was controversial.

Be that as it may, it is clear that the favorite study line is one that is not connected with hormones, so the option of your therapeutic therapy is the most promising. This is a drug baptized as YCT-529What affects the essential substance in sperm synthesis, preventing it from temporarily performed. In animal studies, it was noticed that This is completely reversibleSomething, which would be perfect if it were also reproduced by people. At the moment, the first phase of clinical trials only showed that it was completely safe, but it was one of Checks It is more necessary, so this is great news to continue the investigation.

How does this men’s contraceptive work work?

Men’s contraceptive tablet of your therapy Retinic acid is connected Perform your function. This is the production of the necessary vitamin A for Proper sperm synthesis. If your receiver is blocked, spermatogenesis cannot be done correctly.

In studies with mice and non -mumen primates, three important issues were confirmed. On the one hand that sperm synthesis is suppressed only by a few weeks of introduction: 4 In the case of mice and 2 in the case of non -human primates. In addition, it was noticed that There are only side effects. And finally, it was confirmed that the spermatogenesis Return to normal about 6 weeks after the treatment of treatment.

Thus, this male contraceptive tablet can be sold, it is important to confirm these three key points in people. In March last year, it was announced that the first stage of clinical trials had ended and that the results were good, but so far the publication has not been made. We already know that Check the item Security is more than confirmed.

How did you prove it?

In clinical trials, 16 men from 32 to 59 years old participated. They all presented at some moment VasectomyIn this case, the field only wanted to analyze security, the spermatogenesis was the smallest.

Everyone received one dose that could be from 10, 30, 90 or 180 mg YCT-529The majority acquired her post, although some volunteers were given a dose of 30 mg. Next to food To check whether they affected the consequences of the drug.

No dose caused influence on The heart rate, testosterone levels, inflammatory biomarkers, hormones associated with fertility, sexual desire or mood. In general, there were no side effects. In addition, there were no differences between Post or food consumption.

Therefore, we already know that this male contraceptive tablet is safe at many different levels.

And now?

The next step will be checked How this male contraceptive tablet affects the number of spermatozoa in peopleThis field is already checked in a clinical test, which began in 2024 in New Zealand. More and more volunteers took part in it, as it is normal at the more advanced stages of clinical trials. Specifically, 50 people aged 28 to 70 years.

The results should be announced throughout 2025. If they coincide with the results of the first phase, this male contraceptive tablet will be very close. Perhaps more than any other. The time has come.