Researchers have designed proteins that can directly produce desired actions and use them as the basis for a protein-based nanocomputer. It responds directly to stimuli (inputs) and produces desired actions (outputs).

During testing, the team introduced the engineered proteins into cultured living cells and exposed them to stimuli.

Previously, two inputs were required to produce an output, but the new design provides two possible outputs depending on the order of the inputs received.

Theoretically, the more input data put into the nanocomputer, the more possible combinations and results can be obtained. Inputs may include physical or chemical stimuli and outputs may include changes in cell behavior such as cell orientation, migration, changes in gene expression, and cytotoxicity of immune cells towards cancer cells.

Source: Ferra

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