How does our appetite work? The intestines really play a role in this. Experiments in mice have shown that the stomach and intestines can send signals to a group of CGC cells. These cells are associated with appetite. But this only happens after a few tens of minutes.
There is another group of brain cells associated with the human sense of taste. These are prolactin-releasing hormone (PRLH) cells. And they send a signal to the brain in just a few seconds.
It is known that the sensation of taste in the mouth stimulates the hormone cells that secrete prolactin. They then give the brain the signal: “This is good food, eat more!” and “Slow down, or you’ll get sick!” Ultimately, the balance between these two messages determines snack desire.
It is now hoped that a better understanding of this balance and the interaction between PRLH and CGC cells will help develop new treatments for obesity and weight loss drugs.
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Source: Ferra
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