Russian scientists have successfully completed tests of a drug containing silver nanoparticles intended for treating infections. According to information from the Ministry of Education and Science of the Russian Federation, the experiment on dairy cows showed that the domestic development is more effective than the popular foreign antibiotic.
Experts from Tomsk Polytechnic University (TPU), together with scientists from Mexico and Novosibirsk, found that a drug containing silver nanoparticles reduces the formation of bacterial biofilms, which contributes to better treatment of infections. During the study, a herd of cows was divided into two groups, one of which was given a foreign antibiotic, the other – the Russian drug “Argovit-S, AgNP”. The effectiveness was assessed on the basis of daily biochemical tests, which showed that the use of silver nanoparticles reduced the activity of biofilm formation by 20.4% and 35.6% for various bacteria, while the antibiotic showed the opposite results.
The tests were conducted on cows with subclinical mastitis, a disease that reduces the quality of milk. Both groups were treated until they fully recovered. According to project leader Alexey Pestryakov, the study was the first large-scale study of the effect of silver nanoparticles on bacterial infections in animals and shows the promise of using this approach in the fight against antibiotic resistance. The results of the study were published in the journal ACS Applied Nano Materials and the project was supported by a grant from the Russian Science Foundation.
Source: Ferra
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