The study was conducted jointly by scientists from the New York Stem Cell Foundation Research Institute and Case Western Reserve University. During their work, the scientists created the world’s largest collection of stem cell models from MS patients and studied their behavior.
The study results showed that glial cells in MS patients have unique properties that may contribute to the development of the disease. This discovery contradicts the traditional view that MS is an autoimmune disease caused solely by immune system disorders.
The results suggest that MS may also be caused by processes occurring in the brain.
The scientists also found that certain genes associated with immune and inflammatory function were particularly active in glial cell cultures derived from stem cells taken from MS patients, confirming data from previous studies of brain samples taken from deceased MS patients.
Glial cells generated from stem cells exhibit similar properties to glial cells in the brains of MS patients, indicating that stem cell models closely reflect the processes occurring in the brains of living patients.
Scientists may now be able to explore potential treatments that target glial cells, which could lead to more effective treatments for the disease.
Source: Ferra
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