By making a model of the dynamics of the vasculature, the researchers demonstrated how the vessel adapts to stress. It turns out that the strength of connections within the network depends on the density of the local flow. The problem is that if the flow drops below a certain level, the connection becomes weak and lost. Ideally, this allows the body to adapt flexibly to different living conditions, since less blood is supplied to areas that do not need intensive blood flow.
However, restoring these changes is nearly impossible. And if the plaques clog the vessels, the latter quickly deteriorates. Even if the plates are removed, the functionality of old ships will not be fully restored.