Scientists have worked with the most common in the European population, and a pathogenic version of the F508Del led to a violation of the functions of the respiratory tract. Modern drugs require life -long application and are effective only with certain genotypes that limit their use.
The new approach uses a lined regulatory system that brings only a gap in a DNA gear. This makes the method safer than traditional technologies, and also eliminates the damage of non -buffer effects to the inappropriate sections of the genome.
Researchers have developed and tested 12 modification of the regulatory system on the basal cells of the respiratory tract. A version showed the efficacy of 2.13 times higher than the standard regulator.
Source: Ferra
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