He dream He plays an important role in Body weight controlAlthough we do not pay enough attention. People who sleep little or poorly have more trends to gain weight. In fact, this is usually one of Causes of obesity, Not forgetting its multifactorial character. For example, the reason for this connection between sleep and weight is known. However, new discoveries are still being made. For example, a team of scientists from Central University of South China He found one The hormone of satiety This is a secret mainly when we sleep.
This conclusion supports what we all know: when you sleep badly, you will usually be hungry during the day. In fact, many people act Night trips to the kitchen When they cannot reconcile a dream. And do not eat salad for sure.
Therefore, the knowledge of this hormone of satiety is important. This helps to better understand the reasons why the dream is so important, and also brings scientists a new tool that can be used in the future with Pharmacological goalsThis is soon for this, but the road is made, and these scientists have already begun to walk.
Leptina, Gelin and, now, Raptina
Two of the most famous hormones of satiety Leptin and Grelin. The first promotes a feeling of satiety And increases Sensitivity to insulinSo this contributes to the absorption of glucose in cells more efficiently. Instead La Gelina Increase your appetite. This is usually generated when the brain interprets that we lack energy. For example, when we pass a very strict diet. But it can also be released in other conditions, such as lack of sleep.
In fact, it was clear that when we sleep Leptine release is stimulated And Grelin is suppressedBut in the absence of sleep, the opposite occurs. We already know all this. However, in previous studies with mice, the authors of this new study confirmed that there was another hormone, which, according to the visible, had an article similar to leptin: Raptina
In fact, this hormone of satiety is a fragment that drinks from a protein called Retikulokalbin-2 (RCN2)The RCN2 field is well known for its function in such phenomena as the formation of bones. However, it was not known that this may be due to the control of satiety.
In their first studies, they saw that raptin is a rotation mainly during sleep, and then reduces its levels with a day. Its functions are mainly increasing the feeling of satiety and slowing down the devastation of the stomach. Therefore, there are receptors for RCN2 protein both in the hypothalamus and in the digestive tractWhen RCN2 joins them, a small piece is cut out, freeing a song that removes our hunger from the hypothalamus, and it contributes from the digestive tract that the stomach slowly devastates so that we feel saturated. But what if we do not sleep enough?
New hormone satiety
After checking the influence of Sinit on mice, the researchers wanted to do the same for people. To do this, they had participation 262 peopleOf which 127 were considered clinically obesity. When analyzing their level of sarptinova lower synptin levels And more serious obesity. Those who slept well had the opposite, so it was clear that this song had a clear influence.
On the other hand, these scientists analyzed genetic data 2000 people And they found something curious in people with something known as “Night food syndrome”The field is essentially, this term is used to designate those people who cannot avoid constant traveling to the refrigerator at night.
It was still believed that this is a question Purely psychological And he was treated only with therapy. However, these scientists saw that many people with the syndrome had a rare option The gene that encodes the RCN2 protein. This option leads to the fact that protein can synthesize, but not completely secreted. When this happens, you cannot join your receptors to divide the song. Thus, this is an option that leads to less blue and, therefore, a greedy hunger, which is aggravated at night.
What is used in knowing all this about the hormone of satiety?
Knowing the new hormone satiety is very useful, since it can serve as an approach to future development Medicines to prevent obesity. And this is not only a question of desire or not wanting. Sometimes genes or crazy routine are very complex during the day. Before telling someone that “you are fat because you want”, think twice. In -first, this is the lack of education, and in -secondly, most likely you are wrong.
Source: Hiper Textual
