A team of scientists from Uwan Institute of Virology He just published in Cell Study New coronavirus found in batsThere is no field, this is not the news of 2019 or 2020. This is completely relevant, because it is not SARS-COV 2, calling Covid-19, but from HKU5-COV 2Are there any possibilities of new pandemia now?
To begin with, it is important to clarify that, although we are talking about the new coronavirus, its discoveries were enough years old. It was first discovered in samples of bats cells in 2006. He attracted the attention that his path to cells is the same that uses Sars-Cov 2. Although, apparently, he could not infect human cells. This coronavirus was baptized as HKU5-COV. It seemed that there was nothing to fear. However, the subsequent investigation carried out with Different origin Of these coronaviruses that had the ability to infect human cells. The one that is now known as HKU5-COV 2.
Naturally, everything that happened to the Covid-19 caused great fear New PandemiaThe field to top it all over, it began in Jun, where the first HKU5-COV samples were found. SARS-COV 2, so they started an investigation from which both good and bad news are extracted. But, fortunately, first of all, it is good.
Coronavirus who uses the same castle
All viruses need cell infection to have proteins that act as Receptors For them. They are connected to other proteins located on their surface, very specific, Like the key to the castleA field in the case of a coronavirus causing Covid-19, for example, its key is proteins with a folder, while blocking is Angiotensin 2 (ACE2) Transformed enzymeThis is a protein with a very important role in the circulatory system, which is mainly found in the cells of blood vessels and kidneys. But also in many other organs. For example, it is present in Respiratory and digestive systems.
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In addition to the main function of ACE2 in the circulatory system, it also acts as a SARS-COV 2 receiver, because viral particles can be specially connected to it. Thus, the scientists of the Ujan were very worried to make sure that the path that HKU5-Cov penetrated into bats was precisely the ACE2 protein.
The good news is that these proteins are different between species, so the same virus can infect some, but not others. ACE2 is very different between bats and people, so initially it did not seem that he could infect people. But for some other studies there was enough to find that the new coronavirus line, which is associated with Human Ace2
Better or worse than the Covid-19 virus?
To check the risk of this coronavirus for people, the authors of the newly published study made him in contact with several Cultures of human cellsThe field was cells from the respiratory and digestive system, some with ACE2 on its surface, and others without it.
It was evident that when Ace2 was, Hku5-Cov 2 has the ability to infect the cells and reproduce in them. When there is no protein, they cannot do this. These are the first bad news. Yes, he can infect human cells, namely the same path as the Covid-19 virus. The second bad news is that there is several types More for those who can infect, so this can already be moved in nature.
But there are some good news. Firstly, it is less effective, joining ACE2 than SARS-COV 2. This indicates that it will be a lot Less virulentSo it would be more difficult for the emergence of pandemia. Two other news is related to treatment. And it was evident that this coronavirus was very vulnerable to both specific monoclonal antibodies and some antiviral drugs, such as Sedivir and Nirmatrelevilr. Therefore, if the virus really became infected with people, it would be much easier to stop their expansion than using Covid-19.
It is important that scientists are Avizor’s eye. Meanwhile, panic should not spread among the population. The largest of good news regarding this coronavirus is that researchers have foreseen their movements. If this happened to Sars-Cov 2, another rooster could sing.
Source: Hiper Textual
