We are in times AntihistaminesThe field of this spring is strong in places such as Spain, where rains in March gave rise to an explosion Flowers and pollen What was now translated into a large wave of sneezing, rooster and rupture. Many people take these medicines, but even today, when they do this, they suffer from if the medicine does not allow them to perform the tasks of the day without falling asleep. And it is true that traditionally drowsiness was considered one of the most common side effects of antihistamines. In fact, it was sometimes recommended to take them at night to take advantage of this effect for We reconcile a dream.
However, today we see that many times our doctor prescribes antihistamines during the day to compress his advantages more. When we are guided, we begin to accept them, fearing not to pay at work, but gradually we understand that they no longer give so much dreams. Why?
The key is that there are two types of antihistamines: The first and second generation. The first, the oldest, are those that usually cause drowsiness. On the other hand, the latter, even capable of letting a little sleep, do it with a lot of less. This does not mean that the first generation is no longer prescribed. It depends a lot on the matter. Now, if you want to know the generation of the drugs you take, visit what will happen next.
First of all, why antihistamines?
Histamine is a substance that is released in the threat of some cells of the immune system, known as Oblast cellsA field among other functions, it is responsible for the deposition of blood vessels, so that much more leukocytes can go to the place of infection. It also contributes to the production of mucus in order to maintain this possible threat and cannot advance through the respiratory tract.
The problem is that sometimes our immune system is confused and is found as a threat that is not. For example, pollen. This occurs when an allergy occurs when histamine is responsible for most of the symptoms. This is the reason why drugs are used, called antihistamine drugs that are responsible for blocking the receptors to which histamines are connected. They are produced, but they cannot fulfill their function, because the receiver, which connects to cause their consequences, is busy.
Why do some give sleep, but others do not?
It should be noted that histamines have many other functions outside their role in the immune system. For example, they have a very important effect on the digestive and central system, when they intervene in processes such as Training and memoryIn addition, they help to regulate sleep. That is why the histamine receptors are actually detected in many types of cells, but especially in the recipes of the central nervous system and its periphery.
The first generation antihistamines had the ability Cross the hematoencephalic barrierThe field is a selective barrier that allows certain substances, such as water, oxygen, carbon dioxide and general anesthetics, to reach the brain, but at the same time blocks the passage of pathogenic microorganisms and harmful substances.
When crossing this barrier, the first generation antihistamines have the ability to achieve depth The central nervous system And there are also blocking the receptors involved in sleep regulation. That is why they cause so much drowsiness.
The second -generation antihistamines, on the other hand, barely overcome the bloody brain barrier. So much, therefore, they give a little sleep, but nothing to do with others.
Some examples
If you take Chloropheniramine, diphenhydramine or hydroxycinMost likely, this will lead to you drowsiness, as they are first -generation antihistamine drugs. Instead, if you have been prescribed Bilastin, Cetirizin, Dramuzin, Ebastin, Fexofenadin, Levo -Sotirizin or Laratadin You will be less sleepy because they are a second generation. Currently, orally, they are usually always recommended as a second generation; Thus, in fact, allergy tablets no longer give so many dreams. If your doctor does not indicate otherwise, there is no problem in order to take them throughout the day.
Source: Hiper Textual
