These scientists could find out how to strengthen the bones for life

With an ever higher population level, cases osteoporosis increase around the world and get the need Find new medicines to strengthen the bonesThe field and it is wonderful that the expectant life expectancy in many countries continues to grow, but the ideal is that those people who are aging do it with Health and autonomyThe field for this to happen, the bones are a key point on which you can concentrate enough attention.

Among them are a team of scientists from Leipzig UniversitySince they have just published a very interesting study in this regard. Before continuing, it is important to clarify that the study This was done in miceSo you cannot know if it will be extrapolated for people. Despite this, if it is achieved, we would face something very promising.

And this is that these researchers have found a substance that can imitate natural mechanisms that help maintain strong bones in young people. Imitation of these processes would be very useful for preventing osteoporosis and strengthening bones For life. Acting will no longer be synonymous with bone weakness.

How does the molecule work to strengthen the bones that osteoporosis prevents?

There are two types of cells involved in their growth in the bone, either positively or negatively. On the one side, Ostoroblasti They form the bones of the cell, and on the other – Osteoclasts Interior in degradation, reabsorption and remodeling. When osteoporosis occurs, the activation of the second cells increases greatly compared to the first. Therefore, more bones are usually degraded. To strengthen the bones, it is necessary Return this processField and here enters the game molecule GPR133.

GPR133 is naturally activated when there is Mechanical voltage to bonesAnd also for Interaction with neighboring cellsWhen such activation occurs, the signs of a waterfall are launched, which leads to Ostoblasts stimulation and osteoclast inhibitingThe field unfortunately, this is a process that breaks up with age. But if it can be stimulated?

The authors have just been published AP503 which can activate the GPR133 without the need for bone tension or stimulation of the neighborhood. Imitate the natural effect. In previous studies, it was noted that this is a molecule capable of stimulating and strengthening Skeletal muscleA field but could you do the same with the bones? And, more importantly, can osteoporosis prevent?

According to research on mice, yes

When trying to influence this mouse molecule, it was possible to strengthen their bones for life, even when they had already had Clear signs of osteoporosisThe field of the bones of the rodents was increased, and bone degradation was avoided. All of them are advantages.

These scientists believe that if the results are extrapolated for people, this would be an interesting treatment as for those who already have osteoporosis and strengthen the bones of people predisposed to it. It will be, for example, a case Menopausal women. There is a lot of investigation; But, if ahead, excellent news can be extracted from this study.