New compound can fight 200+ superbug species

Researchers at the University of Illinois in the United States announced that they had discovered an effective compound in the United States. Fights over 200 types of antibiotic-resistant bacteria. The innovation was described in a study published in the scientific journal ACS Center ScienceWednesday (10).

Developed from the modification of the antibiotic Debio-1452 used in the treatment of some bacterial diseases, are you fabi inhibited the reproduction of pathogens that cause serious infections in the lungs, stomach and urinary tract. It has been successfully tested in infected mice.

as well as preventing super bugs The substance that spread throughout the body, reducing the amount to pre-infection levels, had another advantage. In tests, the compound did not have a significant effect ongood bacteria”, preserving the gut microbiome.

Although the results placed fabimycin as a candidate for use new antibiotic, It has not yet been tested on humans.. For the next steps of the research, the team led by Paul J. Hergenrother, professor of chemistry at the American university, is dependent on funding.

threat to human health

hour drug resistant bacteria It is caused by mutations caused by misuse of antibiotics, among other factors. The World Health Organization (WHO) regards such pathogens as a “great threat to human health” and advocates the immediate development of new drugs to combat them.

are classified as gram negativepresents a cellular structure that prevents the advent and accumulation of antibiotic molecules. already gram positive bacteriaThose that have already been treated with Debio-1452 do not have this outer layer.