Scientists investigate tomato and potato compounds for cancer treatment

Medicinal plants, which have been part of the oral tradition of different cultures for thousands of years in the treatment of diseases, are the subject of a study conducted by Polish scientists from Adam Mickiewicz University. they argue that Future drugs against cancer are formulated with the use of glycoalkaloids found in plants of the family. Solanaceae🇧🇷

According to lead researcher Magdalena Winkiel, a PhD student at Adam Mickiewicz, although treatments are improving every day, their side effects often damage healthy cells in patients.

Therefore, the chemist and neurobiologist said in a statement that what scientists around the world are looking for are “drugs that are lethal to cancer cells, but also safe for healthy cells.”

making herbal medicines

There are five main glycoalkaloids investigated by Winkiel’s team: solanines, chaconines, solasonines, solamargines and tomatoes🇧🇷 All these substances are found in extracts from the plant family. Solanaceae🇧🇷 These vegetables are popular and are found on the tables of many people around the world in the form of tomatoes and potatoes.

Studies in silico (computer simulation), solanine and chaconine potato gifts They have lethal functions against leukemia cells and anti-inflammatory properties, and they have the potential to treat sepsis by acting directly on cancer stem cells.

Finally, bland tomatoes offer a natural protective potential for the human body, with tomatine acting as a body cell cycle regulator to kill malignant cells. Now, studies in a laboratory setting and animal models will be used to determine the efficacy and safety of the treatment before testing it in humans.

ARTICLE 🇧🇷 Boundaries in Pharmacy – DOI: 10.3389/ffhar.2022.979451.