Scientists from Sechenov University of the Russian Ministry of Health presented a monograph in which they examined how myocarditis develops in people with coronavirus infection and post-covid syndrome. It was the first in Russia and one of the first in the world to describe in detail the causes and mechanisms of this disease associated with the COVID-19 epidemic. The authors of the monograph are Professor Evgeny Kogan and Professor Olga Blagova.
This scientific article describes a new health condition that has arisen as a result of the pandemic – acute coronavirus myocarditis. Scientists confirmed its existence by extracting the RNA of the virus from the affected tissues of the heart and blood vessels. These samples were obtained during postmortem autopsies. According to autopsy data, coronavirus myocarditis was detected in 60% of patients who died from COVID-19.
For the research, the scientists conducted extensive work, including analysis of tissue taken both after death and during heart surgery. These methods included immunohistochemistry to detect markers of innate immunity, viral myocarditis, and viral proteins in heart tissues, and polymerase chain reaction (PCR) to detect viral RNA in tissues.
Experts note that coronavirus myocarditis can mimic coronary heart disease, since inflammatory processes occur simultaneously in the myocardium and blood vessels. The monograph developed by these researchers may be useful not only for physicians but also for students and young scientists as it reveals the pathogenetic mechanisms that may contribute to the search for new treatment modalities.
Source: Ferra
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