The study, published in the journal Biological Psychiatry Global Open Science, analyzed data from more than 40,000 UK Biobank participants and combined brain imaging results of 32,094 people with smoking history and genetic risk information.
The results showed a strong correlation between daily smoking and shrinkage of brain volume, with more smoking leading to an even greater shrinkage. The most significant effect was observed in total gray matter volume; This reveals a clear dose-response relationship with the number of cigarette packs smoked per day.
Surprisingly, the study showed that these changes in the brain were irreversible and persisted even in smokers who quit smoking years ago.
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Source: Ferra
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