To create mini kidneys with blood vessels, scientists combined kidney organoids with vascular organoids. The union of organelles triggers the interaction process between them, resulting in the formation of the circulatory system.
The authors of the study see many promising areas for applying their development. First, mini-kidneys with blood vessels would allow more accurate modeling of various kidney diseases, such as autoimmune diseases or diabetes. Second, these organoids could form the basis for the development of new treatments for kidney diseases.
Third, the technology can be used to create other types of organoids with circulatory systems. In the future, scientists plan to place mini kidneys with blood vessels on a microfluidic chip to conduct more complex studies. This will make it possible to simulate conditions that occur during serious diseases, as well as connect mini-kidneys to other organoids, for example, heart organs.
Source: Ferra
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