A study conducted by scientists from the China University of Pharmacy identified a new class of metabolites called terpene-nonadride heterodimers, specifically bipoterpyrids. Among the twelve compounds discovered, Bipoterpide No. 2 showed “impressive efficacy” in killing cancer cells by inhibiting the enzyme DCTPP1, which is associated with tumor growth and treatment resistance.
Unlike traditional treatments that often cause toxic side effects, Bipoterpide No. 2 effectively shrank tumors in mice without causing harm. By blocking the DCTPP1 enzyme, the compound disrupts the metabolism of cancer cells and helps suppress tumors. This discovery opens a new avenue for targeted therapies for colorectal cancer, one of the deadliest cancers in the world.
With further development, bipoterpid 2 may become a promising drug candidate, offering a safer and more effective alternative to traditional chemotherapy.
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Source: Ferra
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