Ribosomes are molecular “machines” that synthesize proteins. Previously, all ribosomes of an organism in the cell were believed to have the same composition. Scientists of the Moscow State University of Moscow protected the yeast, the mythoribosomes of the organelles, their genome and a protein synthesis system.
For the experiment, the researchers changed the genes of the chosen ribosomal proteins by adding a “label ında firmly connected to antibodies. This made it possible to distinguish fractions by specific proteins by Mitoribos and perform quantitative proteomic analysis. The results have shown that different ribosome factions contain a different protein set.
The next step will be to examine the functional meaning of this phenomenon by using structural research.
Source: Ferra
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