To do this, the researchers analyzed DNA methylation profiles from tissue samples from 100 women and 100 men over the age of 90.
As a result, scientists have identified genes that may be unique to Russian centenarians. These are PRG3 and SERPINB2. They showed a statistically significant change in activity.
Also, scientists from the Laboratory of Aging Immunology of the Russian National Research Medical University compared the immune status of 250 centenarians. Only 10% had the healthy aging phenotype and did not have frailty syndrome.
Source: Ferra

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