The US is close to approving a drug that increases the lifespan of large dogs

FDA Nears Approval a drug that can prolong the life of large dogs, which is significantly shorter than that of a small breed. The drug was developed by Loyal, a biotechnology company that develops treatments that not only prolong life but also maintain the quality of life of dogs as they age.

According to a study conducted American Kennel Club, The lifespan of large breed dogs ranges from 8 to 12 years.. On the other hand, small dogs are between 10 and 15 years old; Some smaller dogs even live up to 18 years. This is a significant difference, although Loyal argues that It’s not something inevitable. This is actually due to some type of “genetically linked disease caused by historical artificial selection” and therefore this is what This can be treated with medications.

That’s the name of the drug LOY-001. We reiterate that this has been approved by the FDA, stating that it agrees that “has a reasonable expectation of effectiveness”. This does not mean, however, that the Food and Drug Administration has already reviewed its use and distribution. This means the data provided by Loyal demonstrates that “there is a reasonable expectation of effectiveness” in large dogs.

The FDA’s Center for Veterinary Medicine reviewed Loyal’s data, results and scientific arguments and determined that they provide reasonable grounds to believe that the drug will be effective in extending the lifespan and health of dogs. Pending successful completion of the Manufacturing and Safety sections, Loyal will receive conditional approval for LOY-001, which will allow them to market the drug to extend the life of large dogs.

Loyal.

How does a drug that can prolong the life of large dogs work?

According to Loyal, selective breeding of large breed dogs causes Up to 28 times higher levels of growth hormone IGF-1. than in small breed dogs. And this significantly reduces their life expectancy. Thus, the drug works by reducing the level of IGF-1 and therefore allows dogs to prolong their life without compromising their health.

Loyalists claim that the drug clinical trials are yet to be completed. It is also emphasized that this is a long-acting drug. Therefore, it should be administered to large or giant breed dogs every three to six months. They also hope the FDA will give final approval by 2026.after which they can begin distributing it.