Scholars believe that the discovery of a new blood subgroup is useful for doctors and nurses in case of difficulties in diagnosing the patient. Forty years ago, the death of two babies prompted scientists to investigate a rare blood subgroup. A subgroup called Er that is now paving the way for new options from prevention relates to similar tragedies. The focus of the study was on ABO blood group systems and Rh factors. These are foundations for transfusions of blood.
Cell surface antigens and their variants are numerous and complex. It was discovered in 1982, then Erb version was discovered in 1988. The Er3 code was used to describe the absence of Era and Erb. When our body detects the presence of an antigen that is not ours, then immune system activates. Antibodies are sent to signal the destruction of cells with foreign antigen.
British researchers analyzed the blood of 13 patients with suspected antigens. Here are the variants found in the Er antigens: Era, Erb, Er3, Er4 and Er5. Due to the genetic codes of the patients, it was possible to gene encoder of the protein related to the cell surface. It is called PIEZO1 and with this study it was possible to underline the potential antigenicity of little known proteins and their importance for transfusions.
Source: Lega Nerd
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