Scientists at the Kitano Medical Research Institute in Osaka have scheduled a July 2024 clinical trial to grow new teeth in humans. occurrence in the experiments will involve people with agenesis, a genetic disease that leads to tooth loss. If everything is completed successfully, by 2030 open trials for everyone will begin.
The head of the study, Katsu Takahashi, wrote about growing teeth to replace those lost since the days of graduate students. And he was darkened that he would succeed, because this mechanism was created long ago by nature itself and works in different animals, such as crocodiles and sharks. Technically, the human body already has the full development of new teeth, but this ability is blocked at the genetic level, so scientists needed to crack the genetic code.
The solution was found and tested on rodents. The USAG-1 gene interacts with proteins and captures signaling to them, including bone morphological protein. This protein causes tooth growth, so only a small amount of USAG-1 is needed. A suitable antibody was found in 2018, and at the same time it turned out that they were able to grow new teeth in ferrets, which turned out to be useful for teeth.
Although he is confident of success, Takahashi acknowledges that adapting the techniques for humans can be a bit of a search. Or the resulting dangerous consequences, such as uncontrolled growth of teeth. This is how hair evolution has been shaped by the well-preserved and post-professional look of hair. provided.
Source: Tech Cult
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