The study identified the amino acid threonine as a promising metabolite that may extend life under certain conditions. Threonine has previously shown protective properties against diabetes in mice and is also important for collagen and elastin production, blood clotting and fat metabolism.
The team confirmed their findings by combining data from the UK Biobank with metabolomic data from 160 fly species. Threonine has been associated with healthier and longer lives in certain genetic and dietary groups. Interestingly, another metabolite, orate, showed a negative effect on lifespan.
This technique could revolutionize aging research by focusing on metabolites relevant to both flies and humans.
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Source: Ferra
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