Arteriviruses currently infect animals such as pigs, horses and primates but have not yet been found in humans. But their ability to cause long-term infections and evolve across hosts raises concerns about possible infection in humans, the scientists report.
In experiments, they blocked the FcRn receptor using a monoclonal antibody, effectively preventing infection in host cells, suggesting a potential treatment. Cody Warren of Ohio State University, one of the authors of the study, emphasizes that humans are “immunologically naïve” to arteriviruses, which can make transmission particularly dangerous.
The results of the study may form the basis for future prevention strategies against these viruses.
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Source: Ferra
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