Organoids (small tissue models grown from stem cells) are of tremendous value in disease and potential transplant research. However, assessment of their progress has been slow and inconsistent.
The study, published in the journal Communications Biology, focused on hypothalamic-pituitary organelles that produce ACTH, a hormone essential for regulating stress and metabolism. Researchers have found that high levels of early expression of the RAX protein generally lead to better ACTH production later on.
The team trained their AI model on 1,500 organoid images. Combining the EfficientNetV2-S and Vision Transformer models, the AI achieved 70% accuracy, outperforming experienced researchers who managed to achieve less than 60%.
The AI also successfully classified non-genetically modified organoids, identifying those most likely to produce high-quality results.
Source: Ferra
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