In the study, 94 patients, including children, were analyzed using a new method (digital droplet PCR). The results showed that the level of donor DNA in the patient’s blood is usually very low but rises sharply in case of rejection. This makes it possible to accurately rule out or confirm rejection with a simple blood test.
Currently standard practice is to regularly take biopsies (tissue samples) of the transplanted heart. This is a very painful procedure that carries risks for the patient, especially for children who need to have a biopsy performed under general anesthesia. However, this diagnostic method is expensive and requires frequent visits to specialist clinics.
The new blood test is significantly cheaper and more convenient. Patients will be able to donate blood at health centers and samples will be sent by mail for further analysis.
Source: Ferra
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