This type of tumor causes a strong increase in blood pressure. Currently, only about 100 cases of this disease have been recorded in the world.
Reninoma consists of juxtaglomerular cells that produce excessive amounts of renin, leading to the development of hypertension.
Although the tumor is mostly benign, it can cause serious complications, including metastasis.
Scientists from the Sanger Institute and other medical institutions in the UK have discovered a specific error in the genetic code of NOTCH1, the famous ‘cancer gene’ behind the development of reninoma.
This gene is associated with various types of cancer. The researchers hope their discovery will help develop new treatments for reninoma, especially for patients for whom surgery is not an option.
Source: Ferra
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