The study focused on PM2.5, microscopic particles less than 2.5 microns in diameter that can penetrate deep into the lungs and even cross the blood-brain barrier. Vehicle exhaust is a significant source of PM2.5 in urban areas and poses a significant health threat as well as respiratory problems.
Researchers examined brain tissue samples from deceased people, analyzed levels of amyloid plaques and correlated them with PM2.5 exposure levels in residential areas at different times before death. They found a clear relationship: People with higher levels of exposure to PM2.5 had significantly higher levels of amyloid plaques. Interestingly, the study found a stronger link between air pollution and plaque formation in people lacking the ApoE4 gene, a known risk factor for Alzheimer’s disease. This suggests that air pollution may be an important factor in the development of Alzheimer’s disease, especially in those without a genetic predisposition.
Although more research is needed to confirm the cause-effect relationship.
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Source: Ferra
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