Comparable to traditional PCR tests in accuracy, these strips provide rapid, on-site disease detection. Unlike PCR tests, which require specialized equipment and experience, these strips are easy to use and similar to traditional rapid antigen tests.
The strips work using DNA nanorings and CRISPR/Cas proteins. These proteins, known for their role in gene regulation, are programmed into specific DNA sequences. If the target is present, the nanorings are destroyed, triggering a cascade reaction that is easily detected by the test strip even with minimal amounts of target DNA.
The applications of this technology are very broad. Another researcher, Fei Deng, believes the strips could speed up responses to emerging diseases, track antibiotic resistance and help protect endangered species.
The team is currently working with Australian industries to establish local manufacturing and explore a range of applications.
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Source: Ferra
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