Moderna’s vaccine, mRNA-4359, aims to stimulate the immune system to attack and fight cancer cells. The vaccine works by presenting tumor markers to the immune system, potentially increasing its ability to recognize and attack cancer cells. Trial results showed that the treatment induced an immune response and was well tolerated, with side effects including fatigue, pain at the injection site and fever.
Specifically, eight of the sixteen patients whose responses were evaluated did not experience tumor growth or new tumor development.
The trial, which is still recruiting patients, is designed to provide more information about the potential of the treatment in combination with the immunotherapy drug pembrolizumab in progressive types of cancer.
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Source: Ferra
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